What we do

Commit Biologics has developed a novel platform technology to harness the power of the complement system, a vital part of the innate immune system. With a unique mechanism of action, the technology has the potential to create a new type of immunotherapy for the treatment of a variety of cancers.

The BiCE™ technology

The complement system represents an efficient immune mechanism for clearing tumor cells, modulating the tumor-micro-environment, and for stimulating an adaptive immune response. However, complement is inherently difficult to activate and is currently underexploited in cancer treatment. The BiCE™ technology is designed to potently activate the complement system to induce tumor cell killing. It’s based on bi-specific antibodies that specifically recruit the complement system to the cancer cells. With a novel mechanism of action, the technology has the potential to redefine cancer treatment.